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KMID : 0388219950020020207
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Journal of the Korean Rheumatism Association
1995 Volume.2 No. 2 p.207 ~ p.211
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A Case of Chorea Associated with Antipholipid antibodies in Patients with Systemic Lupus Erythematosus
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조영석
최범순/여경아/양형인/박성환/이상헌 조철수/기호연
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Abstract
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The neuropsychiatric manifestations of systemic lupus erythematosus 9SLE) are diverse but, among them, movement disorders such as chorea, ataxia are uncommon.
We describe a 16 year old female SLE patient with positive anticardiolipin antibody who developed sudden onset of chorea. The clinical and laboratory findings that positive anticardiolipin antibody, thrombocytopenia, chorea were suggested
antiphospholipid syndrome. Although the pathophysiology of chorea in SLE is unknown, an association with antiphospholipid antibodies has been suggested. The underlying pathogenic mechanism of this case could not established but was most likely to
have
been an ischemia of the contralateral subthalamic nucleus. She was treated with corticosteroid, haloperidol and warfarin and now chorea is disappered.
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KEYWORD
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